Mental Disorders

How Defective DNA Repair Triggers Two Neurological Diseases

Scientists at St. Jude Children’s Research Hospital have teased apart the biological details distinguishing two related neurological diseases — ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS). Both disorders arise from defects in a central component of the cell’s machinery that repairs damaged DNA, but each disease presents with distinct pathologies. Defects in DNA [...]

Epilepsy Linked To Higher Risk Of Drowning

People with epilepsy appear to have a much higher risk of drowning compared to people without epilepsy. Previous studies have shown a higher risk most likely due to seizures but this study is one of the first to show exactly how high the risk may be. For the study, researchers compiled information from 50 studies [...]

Rare Genetic Disorder Gives Clues To Autism, Epilepsy, Mental Retardation

A rare genetic disorder called tuberous sclerosis complex (TSC) is yielding insight into a possible cause of some neurodevelopmental disorders: structural abnormalities in neurons, or brain cells. Researchers in the F.M. Kirby Neurobiology Center at Children’s Hospital Boston, led by Mustafa Sahin, MD, PhD, and Xi He, PhD, also found that normal neuronal structure can [...]