Colon Cancer Symptoms and Treatment

Oral Xeloda Plus Oxaliplatin Is Comparable To FOLFOX As Colorectal Cancer Treatment

Overall survival results from a 14-month follow-up of the international, Phase III NO16966 study confirm that oral Xeloda plus oxaliplatin (XELOX) is comparable to a current standard treatment, FOLFOX-4 (infused 5-FU/leucovorin plus oxaliplatin) in the first-line treatment of advanced (metastatic) colorectal cancer. In the study, patients receiving XELOX lived for a median of 19.0 months, [...]

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Colorectal cancer screening rates still too low

Although colorectal cancer screening tests are proven to reduce colorectal cancer mortality, only about half of U.S. men and women 50 and older receive the recommended tests, according to a report in the July 2008 issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research. The Centers for Disease [...]

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GeneNews Launches Blood Test For Colorectal Cancer Screening

GeneNews Limited announced the launch of ColonSentry, the world’s first blood-based molecular test for colorectal cancer screening. ColonSentry is a blood test that assesses a patient’s current risk of having colorectal cancer, identifying those in the asymptomatic general population with increased risk who might benefit from further more invasive diagnostic testing such as colonoscopy. This [...]

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Most Adults Don’t Realize Activity Lowers Colon Cancer Risk

Many experts now consider colon cancer a largely preventable disease, but a new study finds that primary care doctors might not always inform patients about one important step they can take to reduce their risk: becoming more physically active. When researchers analyzed survey data from 1,932 adults who answered questions about colon cancer risks, only [...]

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Get Screened For Colon Cancer

The Nebraska Department of Health and Human Services and other partners are kicking off a special promotional campaign targeting Nebraska men and women over 50 who haven’t been screened for colon cancer. “It’s a challenge to get men screened. This new promotional campaign is designed to get their attention through something that gets their attention—sports,” [...]

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Colon Cancer Linked To Unequal Gene Activity

Researchers here have discovered that a subtle difference in the activity of a pair of genes may be responsible for one of every 10 colon-cancer cases. The work, led by researchers with the Human Cancer Genetics Program at Ohio State University’s Comprehensive Cancer Center, is the first to link this particular gene conclusively as a [...]

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A New Opportunity For Colon Cancer Prevention

More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer. This theory, called the two-hit hypothesis, guided scientists around the globe [...]

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Many Colorectal Cancer Survivors Do Not Receive Recommended Care

A new analysis reveals that fewer than half of older patients successfully treated for colorectal cancer receive the recommended screening schedule to detect any recurrence of cancer. The study, appearing in the October 15, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society, indicates poor compliance to recommended monitoring of colorectal cancer [...]

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Researchers Identify Cancer-Causing Gene In Many Colon Cancers

Demonstrating that despite the large number of cancer-causing genes already identified, many more remain to be found, scientists at Dana-Farber Cancer Institute have linked a previously unsuspected gene, CDK8, to colon cancer. The discovery of CDK8′s role in cancer was made possible by new tools for assessing the activity of specific genes, say the authors [...]

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What is sign for progressive of colorectal carcinoma?

The process of tumor invasion and metastasis is associated with alterations in the functions of several adhesion molecules. In general, tumor cells lose their capacity for normal adherence, which facilitates their detachment from their site of origin. alpha-catenin links E-cadherin to the actin cytoskeleton via its association with either beta- or gamma-catenin. Reduced alpha-catenin expression [...]

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Trial Compares Accuracy For Virtual Colonoscopy, Standard Colonoscopy

Computerized tomographic (CT) colonography, also known as virtual colonoscopy, is comparable to standard colonoscopy, which uses a long, flexible tube with a camera to view the lining of the colon, in its ability to accurately detect cancer and precancerous polyps and could serve as an initial screening exam for colorectal cancer, according to the results [...]

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Screening for Colon Cancer: Just do it

I have a patient who is absolutely phobic about getting a colonoscopy for colon cancer screening. She has a family history of colon cancer so the fear may be about what is “found” or it may just be the anxiety of going through the test. No amount of cajoling on my part or her husbands [...]

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