Breast Cancer

Scientist Presents New Breast Cancer Imaging Method

Flemming Forsberg, Ph.D., professor of Radiology at Jefferson Medical College of Thomas Jefferson University, presents updated results on the effect of using subharmonic imaging (SHI) in determining a breast cancer diagnosis at the Fifth Era of Hope meeting in Baltimore, Maryland. SHI – a new breast cancer imaging technique – appears to improve the diagnosis [...]

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Method Evaluates Variations Identified In Breast Cancer Susceptibility Genes

Using mouse embryonic stem cells, researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have developed a new method to evaluate which mutations, or changes, in a gene known to increase breast cancer susceptibility, may lead to cancer. The new test, called a functional assay, is more comprehensive and reliable [...]

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Value Of Routine Breast Cancer Screenings For Elderly Patients

Although annual breast cancer screenings are recommended for most women ages 40 and older, physicians debate the value of regular mammograms for elderly women, who are more likely to die from unrelated causes, the New York Times reports. A study published in May in the Journal of Clinical Oncology showed that among women ages 80 [...]

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Radiation Treatment of Rare Breast Cancer May Lower Recurrence

Patients with a rare type of breast cancer may benefit from receiving radiation therapy in addition to surgery to prevent recurrence, according to a study in the July issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology. Phyllodes tumors are rare breast tumors that [...]

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Herceptin Targets Breast Cancer Stem Cells

A gene that is overexpressed in 20 percent of breast cancers increases the number of cancer stem cells, the cells that fuel a tumor’s growth and spread, according to a new study from the University of Michigan Comprehensive Cancer Center. The gene, HER2, causes cancer stem cells to multiply and spread, explaining why HER2 has [...]

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Breast Asymmetry After Cancer Treatment Affects Quality Of Life

Most women with breast cancer assume that surgery to preserve their breast will be less disfiguring than a mastectomy that removes the entire breast. But nearly one-third of women reported pronounced asymmetry between their breasts, and that perceived disfigurement greatly affects a woman’s quality of life after treatment, according to a new study by researchers [...]

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Young Women’s Breast Cancers Have More Aggressive Genes, Worse Prognosis

Young women’s breast cancers tend to be more aggressive and less responsive to treatment than the cancers that arise in older women, and researchers at the Duke Comprehensive Cancer Center and the Duke Institute for Genome Sciences %26amp; Policy may have discovered part of the reason why: young women’s breast cancers share unique genomic traits [...]

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Antibody To Breast Cancer-Secreted Protein Blocks Metastasis

Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have made a key discovery about the mechanism of breast cancer metastasis, the process by which cancer spreads. Focusing on a gene dubbed “Dachshund,” or DACH1, they are beginning to pinpoint new therapeutic targets to halt the spread of cancer. Reporting their findings [...]

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Taxotere-Based Chemotherapy Significantly Improved Overall Survival Compared In Breast Cancer

For women with early stage breast cancer who have had surgery, treatment with the investigational chemotherapy combination of Taxotere (docetaxel) Injection Concentrate and cyclophosphamide significantly improved overall survival compared to standard chemotherapy. The presentation reports results with a median follow-up of seven years and has been updated since the last report was published with 5.5 [...]

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FDA Approves New Genetic Test For Breast Cancer Patients

FDA has approved a test that helps in assessing the risk of tumor recurrence and long-term survival for patients with relatively high-risk breast cancer. The TOP2A FISH pharmDx is the first approved device to test for the TOP2A (topoisomerase 2 alpha) gene in cancer patients. The TOP2A gene plays a role in DNA replication. The [...]

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Kosan Initiates Trial Of Alvespimycin In HER2-Positive Metastatic Breast Cancer

Kosan Biosciences initiates Phase 2 trial of alvespimycin, the company’s second-generation Hsp90 inhibitor, in patients with HER2-positive metastatic breast cancer. Alvespimycin has demonstrated the potential to disrupt the activity of multiple oncogenes and cell signaling pathways implicated in tumor growth, including HER2, a key signaling pathway in breast cancer. The objective of the Phase 2 [...]

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Breast Cancer Patients Share Experience At Conference

Young women who have been diagnosed with breast cancer have gathered to share their experiences at a two-day conference in Swansea. Breast Cancer Care Cymru is holding its first Younger Women’s Forum at the Marriott Hotel. Only around 100 women in their 20s and 30s are diagnosed with breast cancer in Wales each year. The [...]

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